Steven Kaplan, MD, Highlights Faster-Acting Sildenafil Oral Spray for Erectile Dysfunction

The following interactions have been selected on the basis

How it Works

They validate Aspargo’s international regulatory strategy and confirm that Aspargo meets the highest standards required to ensure the safe distribution of sildenafil spray.” Aspargo developed the brand name, HEZKUE™, with assistance from its commercialization consultant, Syneos Health, a global biopharma solutions organization, following focus groups and surveys with physicians, pharmacists, and patients. The criteria used to select the brand name included first impressions, spelling and pronunciation, interpretation, attributes, favorite name and recall. Brand names used to market a drug are subject to approval of the respective health authorities in each country. Sildenafil Spray is an oral liquid suspension of sildenafil citrate administered via a spray pump that dispenses 12.5 mg of sildenafil per push. Aspargo uses a metered-dose container that delivers the precise amount of sildenafil citrate per push based on patient need.

Why can Silfin Oral Spray lower blood pressure?

The discreet and easy-to-carry oral spray allows the user to customize dosing and avoid pill splitting or crushing attendant with the traditional tablet medication. Erectile dysfunction is characterized by the persistent difficulty achieving and maintaining an erection sufficient to have sexual intercourse. While the prevalence of ED has been shown to increase with age, a recent study conducted by the Sexual Medicine and Andrology Unit of the University of Florence, Italy, showed that ED in younger men is likely to be overlooked and dismissed without a proper medical assessment. About Aspargo Laboratories, Inc.Aspargo Laboratories, Inc., located in women sildenafil Englewood Cliffs, New Jersey, is a commercial stage, specialty pharmaceutical company. Aspargo’s current focus is to commercialize an oral spray formulation of sildenafil citrate, the active ingredient in Viagra®. of their potential significance and are not necessarily all-inclusive.

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Using this medicine with any of

Erectile dysfunction spray side effects

Hezkue spray can begin working within 10-15 minutes for some men due to its sublingual absorption, compared to 30-60 minutes typically required for traditional sildenafil tablets taken orally. Can I use Hezkue spray if I take blood pressure medication? You must consult your doctor before using Hezkue spray if you take blood pressure medication, as sildenafil can interact with certain antihypertensives and is strictly contraindicated with nitrates. Hezkue spray is formulated with flavouring agents to make it more palatable, with most users reporting a mint or neutral taste that is significantly more pleasant than swallowing traditional tablets. Medicines and Healthcare products Regulatory Agency (MHRA) - Sildenafil guidance and product information: British National Formulary (BNF) - Sildenafil prescribing information: NHS UK - Erectile dysfunction (impotence) overview and treatment: The aggregate German, Irish and Dutch market for erectile dysfunction (ED) market exceeds $175 million Aspargo plans to launch Sildenafil Spray in Germany, Ireland, and the Netherlands under the brand name, “HEZKUE™” Aspargo’s Sildenafil Spray offers a convenient, discreet option for men with erectile dysfunction ENGLEWOOD CLIFFS, NEW JERSEY – JANUARY 24, 2023 – Aspargo Laboratories, Inc.

Hezkue side effects

(“Aspargo”), a privately held specialty pharmaceutical company focused on commercializing innovative formulations of leading tablet medications, announced today that the German Federal Institute for Drugs and Medical Devices has authorized the marketability of “Hezkue™ 12.5 mg per actuation, oral suspension“ in Germany effective as of January 12, 2023. The German market – the largest in the EU – represents an important element of Aspargo’s global expansion strategy. Recently, Aspargo received corresponding approvals in Ireland and the Netherlands. “These product approvals reflect Aspargo’s commitment to quickly expand its global platform to the EU during 2023,” said Michael Demurjian, Aspargo’s Chairman & Chief Executive Officer. “The Marketing Authorizations are an important achievement. the following medicines is not recommended.

About Hezkue Spray

Aspargo is the US and international licensee of the patent rights covering Sildenafil Spray from Farmalider, S.A. of Madrid, Spain ( For additional information, please visit our website at aspargolabs.com Forward-Looking StatementsAll statements other than statements of historical facts contained in this press release are forward-looking statements. Forward-looking statements reflect management’s current knowledge, assumptions, judgment, and expectations regarding future performance or events. Although management believes that the expectations reflected in such statements are reasonable, they give no assurance that such expectations will prove to be correct, and you should be aware that actual events or results may differ materially from those contained in the forward- looking statements. Words such as “will,” “expect,” “intend,” “plan,” “potential,” “possible,” “goals,” “accelerate,” “continue,” and similar expressions identify forward-looking statements.

5.3 Epistaxis

Forward-looking statements are subject to a number of risks and uncertainties including, but not limited to, the risks inherent in our lack of profitability and need for additional capital; our dependence on partners to further the development of our product candidates; the uncertainties inherent in the development, attainment of the requisite regulatory authorizations and approvals and launch of any new pharmaceutical product; the outcome of pending or future litigation or arbitration; and the various risks and uncertainties described in the “Risk Factors” sections of our Confidential Private Placement Memorandum of October 19, 2022. All forward-looking statements are expressly qualified in their entirety by this cautionary notice. You should not rely upon any forward-looking statements as predictions of future events. We undertake no obligation to revise or update any forward-looking statements made in this press release to reflect events or circumstances after the date hereof, to reflect new information or the occurrence of unanticipated events, or to update the reasons why actual results could differ materially from those anticipated in the forward-looking statements, in each case, except as required by law. Sildenafil is used to treat erectile dysfunction (also called sexual impotence). Your doctor may decide not to treat you with this

• Sildenafil spray is a modern alternative for ED therapy.
• It reduces the waiting time before sexual activity.
• The spray is generally well-tolerated with proper use.
• It might be prescribed for specific health conditions.
• The method of administration differs from oral tablets.
• Use of the spray should be coordinated with a doctor.
• It can be used alongside other treatments under supervision.
• The spray dose can be adjusted for optimal response.
• Patients should report any unusual symptoms promptly.
• Sildenafil spray offers privacy compared to other methods.
• Read all warnings and precautions on product packaging.

medication or change some of the other medicines you take.

Substance/Class	Effect on Sildenafil Spray	Recommendation
Nitrates	Potent hypotensive effect	Avoid concomitant use
Alpha-blockers	Increased risk of low blood pressure	Use with caution, under supervision
Alcohol	Enhances side effects	Limit or avoid consumption
Other PDE5 inhibitors	Increased risk of adverse effects	Do not combine

Using this medicine with any of the following medicines is

Product details

Sildenafil should never be used in children for erectile dysfunction. In general, sildenafil should not be used for pulmonary arterial hypertension in children, especially for chronic use. Use of sildenafil oral film is not indicated for use in the pediatric population. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sildenafil in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving sildenafil.

How does sildenafil work (mechanism of action)?

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. usually not recommended, but may be required in some cases.

Important Considerations Before Using Impotence Sprays

Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection.

3. Understand the Root Cause

By controlling the enzyme, sildenafil helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection. Sildenafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. If both medicines are prescribed

• Sildenafil spray offers a non-invasive alternative to injections.
• It promotes blood flow to the penile area.
• The onset of action is usually faster than tablets.
• It is an option for men who dislike swallowing pills.
• The spray may reduce gastrointestinal discomfort.
• Consistent use without medical advice is discouraged.
• Dose titration might be necessary for effectiveness.
• It may be used in combination with other ED treatments.
• Possible side effects include nasal congestion or dizziness.
• Proper storage extends the shelf life of the spray.
• Contact a healthcare provider if adverse effects occur.

together, your doctor may change the

Storage Condition	Temperature Range	Protection Required	Shelf Life
Room Temperature	20-25°C	Keep away from heat and moisture	2 years
Refrigeration Recommended	2-8°C	Avoid freezing	N/A
Exposure to sunlight	No direct sunlight	Store in a dark place	N/A

dose or how often you use one or both of the medicines.

Impotence Spray vs. Other ED Treatments

Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. This medicine is liquid sildenafil citrate available only with your doctor's prescription. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make.

2. Topical ED gels (like MED3000/Eroxon)

For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of sildenafil in children younger than 1 year of age. Safety and efficacy have not been established.